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OCR: is is subject The hypothalamic-pituitary testicular a to a variety of influences. may be the Impairment of gonadotrophin secretion affect the consequence of generalised diseases that hypothalamus and pituitary (e.g. ated craniopharyngioma), or it may be an iso SH is deficiency in which secretion of LH and impaired; isolated hypogonadotrophic r, rarely, hypogonadism can be either congenital an acquired idiopathic defect. See later: Hism · Isolated Hypogonadotrophic Hypogon . Other Causes of Hypogonadotrophic Hypogonadism